Peptidases • Ustilaginomycotina
Annotations/GenomesAcain1Cersp1Exomac1Exova1Hethyg1Jamsp1Malgl1Malsy1_1Meimi1Melen1Moeaph1Monili2Psean1_1Psehu1Rhanym2_1Rhodsp1Spore1Tescy1Tilalb1Tilan2Tillet1Tilwa1Uroocc1Uropr1Usthor1Ustma2_2Ustsp1TotalAnnotation Description
Merops
2171692582061811661381101971851432221491501551691561591901562431601621451681581674,679
971113911176102181185111076118186883487288Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11322111221111111121211111135Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1113Water nucleophile; water bound by two Asp
16101914141513918111126141510161314121015112013151710381Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
22222222221812232222222222259Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
234232133111213231112143Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22332222323322232322232222262Families of peptidase inhibitors not assigned to clans
111115
111111111111121111111123
2433113121111113111133
2221231112121113121321222345Families of metallopeptidases not assigned to clans
88156117759677758779879976678206Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111111111111111121Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
311117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11111111111111111111121Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
649545655558534555556446556140Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
11111389876799999971181071011788713241Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
9453532256474445451156344446128Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
556554445555544455566545556132Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191925202118171419201824181718182019201820201919192018517Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
425334328355432444334545334102Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111211119Serine or threonine nucleophile; N-terminal nucleophile
64995624142152244222724321223138Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9164917459562930645447535155505550516945854957404251541,516Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
24222121222312261212244Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2262123332141221123131211254Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2133232222121121323111221147Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111211111111111111127
10812131091410111071567107891113998108810262
123
1113
221441522342421412313255