Peptidases • Rhizopus microsporus var. microsporus ATCC52814 v1.0
Annotations/GenomesBacci1Hesve1Lichy1Morel1Mucci2Phybl2Rhich1Rhimi1_1Rhimi_ATCC52814_1Rhior3Umbra1TotalAnnotation Description
Merops
4223113042843762532322902722,744
312524283520203322238Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
103445444341Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
403535294529282824293Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
65678664250Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
16123321230Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1211128Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
22122112114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9776127713674Families of peptidase inhibitors not assigned to clans
11
112116
112
11
2125
11112212112
53211112117
111121119Families of metallopeptidases not assigned to clans
261623172818151822183Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
3411110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
45438444339Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
151113121614121311117Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161711151411101617127Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11712956441068Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1121211110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
736510666251Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
32112111315Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
352023173117193218212Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
45335323331Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
22151019151181810128Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
968267557046485371588Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
131211110Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
74547652343Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21331121216Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
116779644458Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
211116Families of peptidases of unknown catalytic mechanism not assigned to clans
21112111111
262324262424172317204
1113
11
11