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Peptidases • Dactylonectria macrodidyma MPI-CAGE-AT-0147 v1.0
Annotations/GenomesDaces1Dacma1Ilyeu1Ilyrob1Ilysp1MarPMI226Neodi1TotalAnnotation Description
Merops
5726336736226773214003,898
17212223231415135Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
13151012121467Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
25292729312018179Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
533543326Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
312111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12111219Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
234441220Water nucleophile; water bound by Gln and Glu; all endopeptidases
234442322Families of peptidase inhibitors not assigned to clans
122117
12115
212221111
111111410
85810124350Families of metallopeptidases not assigned to clans
30283327292022189Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
565652635Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
233352321Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
988889858Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
37363433361426216Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
24293128331816179Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
544444429Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111116Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
335551325Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
26242425282323173Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
51015141611778Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
223334320Serine or threonine nucleophile; N-terminal nucleophile
2121302425817146Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2633023152803121181631,753Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
26303936371220200Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333233219Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, Glu, His
324343423Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
232221214Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
121318121311988
112
1113
11
8135572141