Peptidases • Cercophora newfieldiana SMH2532-1 v1.0
Annotations/GenomesApibac1Bombom1Cernew1Clabul1Lashir1Lasmin1Podan2Podcur1Schves1TotalAnnotation Description
Merops
3133173973113763622953583373,066
222227232829212623221Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
113117Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
22334422325Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
171816172218181616158Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
44334334331Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11112111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111211110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
31116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
54634745341Water nucleophile; water bound by Gln and Glu; all endopeptidases
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
25544333433Families of peptidase inhibitors not assigned to clans
11
11
21212222216
54434744540
56134542131Families of metallopeptidases not assigned to clans
121224141814142211141Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
44444443334Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22233222220Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
77878777866Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
192019172023191918174Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10121511141210149107Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
43343343330Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1121111210Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212324202424222322203Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
46834436745Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
161621162121161921167Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1141061451121371271041391281,112Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1211191213868998Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43443333330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
23233232222Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3216Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
101011111216101316109
112
1243543325