Peptidases • Suillus americanus EM31 v1.0
Annotations/GenomesBoled1Paxru2Rhisa1Rhivi1Sclci1SerlaS7_9_2Suiame1Suibr2Suidec1Suigr1Suihi1Suilu3TotalAnnotation Description
Merops
5052724974222863463425125983714004274,978
6138626439614960254537349863Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
12122111112217Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201219161222151417161413190Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
10410644107678783Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
43221211121121Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
54155Water nucleophile; water bound by Gln and Glu; all endopeptidases
112223222223235Families of peptidase inhibitors not assigned to clans
111126
123
22232122222123
22223222222225Families of metallopeptidases not assigned to clans
241231121911111213121211180Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2111111121113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
123Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1181198811877108106Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161816181715161618141616196Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
14918131815131815131413173Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
21115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55556665558566Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
1411221113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
192121212121212123192220250Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
53652455465656Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Serine or threonine nucleophile; N-terminal nucleophile
1261386910810887105Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9071861077111410194967997841,090Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6521431521131Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43584335446453Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11211111111113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
42234543343340Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111112
12138169106332250218103108861661,220
11
112