Peptidases • Endophytic Fungi
Annotations/GenomesAcema1Altalt1Altro1AnFL0455Annsty1Ascsa1Astsub1Beaba1Biscog1Bisma1Bisme1Bismed1Bissp1Boeex1Cadsp1Chame1ClaNC0930_1Cloro1CodFL1790_1ConPMI546Cornip1Crypto1CtCBS203_1Currey1Cylol1DaFL1419_1DalEC12_1Daldec1Dalgra1DallocAZ0526_2Dalver1DelFL0756_1Denna1DiaPMI573_1FlaPMI526_1Fusco1Fuseq1Fusoxy1Fusre1Fusso1Glonio1Herpot1_1HyFL0543_1HyFL0890_1HyFL1284_2HyFL1857_1HyNC0597_1HyNC1633_2Hyafin1Hymvar1HypCI4A_1HypCO275_1HypEC38_3Hypmon1Hyprub1HyprubER1909_1Hypsub2Ilyeu1Ilyrob1KdCBS826_1Kredeu1LecAK0013_1Lepor2Leptod1Lophiu1Lopnit1_1Loppic1MarPMI226MelPMI1271_1Micbo1Microd1Mictri1Morel_U14_1Morhum1Myrian1NeFL0031_2NeFL0916_1Nemabo1Nemani1Nemdif1NsAK0226_1NsAZ0576_1Olipa1OphPMI507_1Parsp1Pcapi1Perma1Pestal1PhaPMI808PhaeoFL0889_1Phapo1Phcap1Phcapi1Phisc1Pirin1PlePMI138_1Plecto1Plecuc1Pyrly1Rhesp1Rhoba1_1Sepsp1Talpro1TerNC1134_1ThoPMI491_1ThyNC0857_1Trigam1Trigu1Truan1Umbelo1XyAK1471_1XyFL0064_1XyFL0641_1XyFL0804_2XyFL0821_1XyFL1272_2XyFL1777_1XylFL0016XylFL0043XylFL0255XylFL0594XylFL0662BXylFL0933XylFL1019XylFL1042XylFL1651XylFL2044XylPMI506XylPMI703_1Xylacu1Xylarb124340_1XylarbFL1030Xylbam139988_1Xylcas124033_1Xylcube1Xylcur114988_1Xylgra1Xylhe1Xylhel2Xylint1Xyllon1Xylpal124036_1Xylscr1Xyltel121673_1Xylven1Zalva1TotalAnnotation Description
Merops
56238135736538229441936532334233032752540772531649770268234226047335532149134335532833733733930339371252047440351751055237746734834835539336233247043636037937539140245836667362235435630867465737849048132147640036146735031138643337643735240231936038135646026152855040863340426325664826438043441743450318525352740698830138519050729043838033934143041634941837742030534337738238041247271162437540639938737039540241318337329638734041139038952160,292
341519151715182215141313191531202116542515301613211415131414121718383621212322211816161519171515252915171613171914222319192234331635261427151412312320191518162017141817201817242328151818411623221723271033312567182072624211716192122162315171416172118232538232117201719161819719141918171817322,961Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111311111111111211111222111134Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
141210565525666118172710742657644444367845376856465334116344545610123451917995111108115383554154112651188129551715738152186864163444633163615334541011344344542444345211851Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
29272722231924221718181929293717352321152121183123232221192319273235232018222124283420212221201828281921221923232427292322203934332722202822302129252729302022262324172331243326312631232326113519192831202033344132172624253024211921232322262618192324222221333425222323232324212122212327242221303,552Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4443434444443532223433424344444441111232233444444473444444435343443333434476233333335342434642243433432253633242444433444333435424434334443244335445535Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2111111111112211111114111111111112112111111122211111121113422412111121111111112112111112111121123111213111111111111111111211111111211111111175Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22212211111215211211211111221223111111221112211212222111111121231212121415121113131212113221241112111211112211111111122421111112111111112206Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1121111111111112111122Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111198Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
722334173322145942146122233544441612135323345424234444434434435389141212312122121313625111815121134185773224372539133933218924332223123322248520Water nucleophile; water bound by Gln and Glu; all endopeptidases
11311111111111111141111111132Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
45555443545545535554454534433335563333335544454454444444444444455342465487545544543454545544452435443355555446545444454432444444544444444444454454616Families of peptidase inhibitors not assigned to clans
1311122211217
11
211116
1111212110
11
1113
1111112111111111411111111111211111111111247
11
11
12111222222111211122121222132311122112112211212122111222222122122122122122122122111212111212211111211121222112211222122222111112211122221221216
664433323344427241782533366476634882122365653666233665354114455434812353131434434433811164551152342653455931163445524553234434556844345554242435434589
111311111141111121
7354358236441251039872273464423244419862898354325426334443448103331110598462932146688539729387695337443771113211714411061268273535554526544646874355947977756Families of metallopeptidases not assigned to clans
161713191692026191416153420331018382412819161133171716151618717263018161918211326161719171717232017181717182114332718202231281217192016241430352011201819171815185291713212324301814132119201924242210111210399177301619181791518161719131718201919172228111819212120171922815131918202018202,760Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
17724153444458241122312424555555356666765265335551255555555655222312153455155555453151837371112649721111313142552124525233546372165555555154555552573Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11122232222221111132221122222221151121111232222312212222332221121122331232122223212221212122121231111211422222222222222222222223521222212222221265Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
13311111315Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
10669889789910116117101311971095698979979131088879867811878109108881012888101081010119109997101212810911999106887911712687128612871076101113896101010117710811911107101110119101211111011111010101149912912101081,321Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
34222126291633202327222340294117435035161522262127242324212222202637333128353131253422212628232527262624252926302734332323144140263432142927303013914332232273024222224281932352643281819411423233033351172320502220927162922192027282326222522222325232431473525233125222729281026182626242525313,798Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
191015171712151417151514161725830362981120151023141817181718111327152422262730141414121619161414171417171718201631281313820231420171818191627765171513131313141814129162516451099268818161517105221550121792112131516161917151813121014141614152732261617131716161617916121411151617182,437Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
121111111111114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11111117Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
44344424232333433423422344323333336444443344344344334424344333433244443431333324347333343333345344447534224343334444343433343233433444334333333324494Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111111111111112111111