Peptidases • Cryptococcus wieringae v1.0
Annotations/GenomesCryne_H99_1Cryvi1Crywi1Diocr1Fibin1Treme1Trich1Triol1TotalAnnotation Description
Merops
1571711812831811492032151,540
6681065131468Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1442311319Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1415133312141215128Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3217545431Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1121117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Gln and Glu; all endopeptidases
2224222218Families of peptidase inhibitors not assigned to clans
11
11
2124113317
1122222113Families of metallopeptidases not assigned to clans
81810177911989Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
121111119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
123Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
87712789866Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13121010109121288Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10813151310151599Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5557555542Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1720223221202122175Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3325334326Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
1212111110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4036547352315155392Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
23166171146Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3334333325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1121211110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3244442427Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1012815119131391
11