Peptidases • Daedalea quercina v1.0
Annotations/GenomesBjead1_1Cersu1Daequ1Dicsq1Fompi1Gansp1Phchr1Phlbr1PosplRSB12_1Trave1Wolco1TotalAnnotation Description
Merops
4023403194073804503344333213,386
584153444865476240458Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
21212221114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
161313161518131516135Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1579651764877Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21312211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
3381116Water nucleophile; water bound by Gln and Glu; all endopeptidases
9222101522246Families of peptidase inhibitors not assigned to clans
1111111119
433281223
32422152425Families of metallopeptidases not assigned to clans
17910151420142211132Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12111111110Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111511315Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11136Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8978811109979Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
201313131315131517132Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101110151111111212103Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
66566677655Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
211722222223202224193Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
76476655551Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
52421322531233420215Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1521361091361281601131781051,217Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
72353846139Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33344354433Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21111111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
43554443335Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
252110523514171322209
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