Peptidases • Coprinellus micaceus FP101781 v2.0
Annotations/GenomesAgabi_varbisH97_2Agabi_varbur_1Amamu1Amath1Armga1Armme1_1Copci1Copci_AmutBmut1Copmic2Corgl3Fishe1Galma1Guyne1Gyman1Gymch1Gymlu1Hebcy2Hypsu1Lacam1Lacbi2Leugo1_1Macfu1Marfi1Monpe1_1Ompol1Panst_KUC8834_1_1Pleery1PleosPC15_2PleosPC9_1Plicr1Schco3Schco_LoeD_1Schco_TatD_1Trima3Volvo1TotalAnnotation Description
Merops
28728534631864941628729239031227438835861538656128637933816133645545725146532434735232634533634227625912,199
242537194835112015343027285650551638321222251920583024233829273029181,004Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11125Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
221113121121312212311121342322155Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5511113Water nucleophile; water bound by two Asp
181591430131514212017202130202317172913182420182713182119201819149634Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34431797456137610208711699466669898356542471Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
231411133183512131312311221868Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
13421011221511153Water nucleophile; water bound by Gln and Glu; all endopeptidases
4569347683293631255111910715222322239171Families of peptidase inhibitors not assigned to clans
11
218727
11
11
1111116
1111122111122211112231222340
4315455574236846562465432566377633155
2273323312223323123123532322333283Families of metallopeptidases not assigned to clans
1918133628223029351012281617201224241792740411419313231202223221738796Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111111211111111111312111131Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1121121111111411114112911111111452Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
221111111311171211421221111112111152Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9999177789910111013910891241011128109911101091187324Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1817122218132221171018151327132215171614172530152122171819232122149613Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10101210171587111212121514101511129310151881891099121211129387Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111211111111111111111125Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
43113112164128Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6666647575667755559266346566555665189Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
22411111111117Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18182020211619192519242221252423212023172026221723202020232221232716715Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1110461148798510611612712123771065786676946256Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111111111112Serine or threonine nucleophile; N-terminal nucleophile
661014131289201562274414301620109101112122911121211666524458Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9810110510120716899100144104821421502381441909114174441152021859517811912713011613213113277774,339Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
231331228411141412468245518333734413154Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333331234334323443414331323333333197Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
21317Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111211111111111111111111132Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
3364313334444544446143144444244342120Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111111111111111111111132
15155213136109152413181148228713132111151328131211232412121412209647
1113
11
66