Peptidases • Cochliobolus lunatus m118 v2.0
Annotations/GenomesAltbr1Bauco1Cocca1CocheC4_1CocheC5_3Coclu1Coclu2Cocmi1Cocsa1Cocvi1Dotse1Hyspu1Lepmu1Mycfi2Mycgr3Pyrtr1Pyrtt1Rhyru1Sepmu1Seppo1Settu1Stano2TotalAnnotation Description
Merops
2822953353463723413263303473192603443422973052862663243436,060
12132222291821222217101722132610101613335Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
75101012111010104464885397143Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19282628282124272725222827262425272225479Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
334444444353244334368Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12111111132211321126Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111111111111216Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111112111111119Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
223551333322511223149Water nucleophile; water bound by Gln and Glu; all endopeptidases
445555555345555445487Families of peptidase inhibitors not assigned to clans
211111111121122111123
533332323553335324565
225665466233223115468Families of metallopeptidases not assigned to clans
139121211191311139111728141118141216263Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
877777773624763377105Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
121111111111121111121Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
66656666686101065101067131Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16172324262321211917212417192019202222391Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1213109998111110131161210991311196Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333334333433433333360Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
41232222233322213342Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21212119202221202124222421192021212121400Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
10288999883546892498129Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
3111111111111111220Serine or threonine nucleophile; N-terminal nucleophile
910161416131314161010161613141191512247Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8712011412313212711811112512480126119979897871141332,132Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6675564667278666327105Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333333333334322333356Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
221321111222322332237Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
223334343531334434562Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112116Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
15101213151011121414810911101191210216
1113
112
1223123221222122131