Peptidases • Coniophora olivacea MUCL 20566 v1.0
Annotations/GenomesAspnid1Conol1Conpu1Fompi1Paxin1Pilcr1PleosPC15_2Pucgr2SerlaS7_9_2TotalAnnotation Description
Merops
2913684326063883471943462,972
4425910446241361353Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
415Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
33112312144Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1021251328181322150Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
36941092447Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111328Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
41425144Water nucleophile; water bound by Gln and Glu; all endopeptidases
5227322225Families of peptidase inhibitors not assigned to clans
11
11
112
31228
222365121
752233224Families of metallopeptidases not assigned to clans
161717271632911145Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1121117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1124Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
577111095862Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
4021222113171015159Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8141713141081599Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
1667665643Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
4111218Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1720182121201921157Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
410103481444Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
122117Serine or threonine nucleophile; N-terminal nucleophile
4131912101214993Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
6112113411811612756114847Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1651113431Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
1453235326Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2111311111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2341341523Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
314Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
8213221351231622386
11
112
3822143