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Peptidases • Aspergillus dromiae CBS 140633 v1.0
Annotations/GenomesAspdro1Aspfu1Aspni_NRRL3_1Aspnid1Aspor1TotalAnnotation Description
Merops
3722744042914141,755
741541343Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
314210Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
301933679Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1350371034144Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3343316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
3254317Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5755426Families of peptidase inhibitors not assigned to clans
11
11
11
11
32139
324110
11
813771449Families of metallopeptidases not assigned to clans
211315162590Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11125Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
44105730Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3917284026150Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1671681360Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
2351112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
2237Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1820201726101Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6694934Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
123Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
58134939Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1195916461153556Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
31111723Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3321716Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2522314Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
212218Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3223919Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
10111081958
112
11
2114
321838391