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Peptidases • Plectosphaerella cucumerina MPI-SDFR-AT-0117 v2.0
Annotations/GenomesAcral2Plecu1Plecuc1Plecucu2Sodal1Veral1Verda1Verdah1TotalAnnotation Description
Merops
1964454174392182903063292,640
821171910171314119Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1323111113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1834112222Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
1620192316151720146Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3332322220Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21115Water nucleophile; water bound by Gln and Glu; all endopeptidases
5454343331Families of peptidase inhibitors not assigned to clans
112
2121122112
2222233420
3441214
2233211115Families of metallopeptidases not assigned to clans
1130242712191923165Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
4119106781065Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2232222217Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
7888877962Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1636303419222627210Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
81716189991096Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3444454533Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
33222214Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2126242523212526191Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2754373435Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111216Serine or threonine nucleophile; N-terminal nucleophile
1111116Families of serine peptidases not assigned to clans
72425268121315130Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
481701681766096110113941Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
18108155745Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3343333325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
3333233323Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2222122215Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1211881014131288
31312212