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Peptidases • Sporopachydermia lactativora Phaff 68-199 v1.0
Annotations/GenomesAscru1Babin1Canar1Cante1Debha1Dekbr2Hypbu1Metbi1Picme2Picpa1Sacce1Spola1Wican1Yarli1TotalAnnotation Description
Merops
1551711411511511431531421341281371531822122,153
10121210661012610871235156Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111111129Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1417121313151514131115191814203Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
9422234222234243Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12111219Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
4434333424244347Families of peptidase inhibitors not assigned to clans
112
11
112
11111121211
2222222222324231
111211111111114Families of metallopeptidases not assigned to clans
91386561166676610105Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1221111112121219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6767776786576792Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
814101414141211118981913165Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5467494473456472Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
3244343352253447Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1916161818181816191820181920253Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
233612233823442Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111111111213Serine or threonine nucleophile; N-terminal nucleophile
73333343333341459Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
3145303436273529242625334444463Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11114212114Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4333333333333343Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
121217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3332342223234238Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111114
87691011911899111013131
112
1111132111
22
112