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Peptidases • Aspergillus puulaauensis IBT 32284 v1.0
Annotations/GenomesAspfu1Aspni_NRRL3_1Aspnid1Aspor1Asppuu1TotalAnnotation Description
Merops
2744042914144201,803
415413743Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
142411Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
193363180Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5037103422153Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3433316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2543317Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
7554425Families of peptidase inhibitors not assigned to clans
11
11
11
21339
241310
11
1377141354Families of metallopeptidases not assigned to clans
131516251786Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11215Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
41057531Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1728402642153Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
7168131862Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3511212Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
23611Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020172623106Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6949634Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1214Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
81349438Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5916461153136573Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11117727Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3217518Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
5223315Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
122128Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2239420Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
1110819957
123
11
112
183833190