Peptidases • Pyrenochaeta sp. DS3sAY3a v1.0
Annotations/GenomesAltbr1Cocca1CocheC5_3Coclu2Cocmi1Cocsa1Cocvi1Pyrsp1Pyrtr1Pyrtt1Settu1Stasp1TotalAnnotation Description
Merops
2823353723413263303474312973053244544,144
122229182122222013261616237Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
71012111010101088912117Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192628212427272826242232304Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34444444444447Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111111111112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111112111214Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
23513332113128Water nucleophile; water bound by Gln and Glu; all endopeptidases
45555554555457Families of peptidase inhibitors not assigned to clans
21111111221115
53323233354642
25654665235655Families of metallopeptidases not assigned to clans
131211191311132014111220169Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
87777777767784Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111111211113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
66666665656569Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
162326232121193219202229271Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
121099811111112101313129Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
33343333333337Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
42222223223329Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212120222120212019202122248Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
108999881089912109Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
3111111111113Serine or threonine nucleophile; N-terminal nucleophile
91616131314161013141513162Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8711413212711811112518797981141941,504Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6756466176621384Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333333223334Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
21211112222219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
23343433344541Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
151215101112141211101212146
112
11
231232222625