Peptidases • Hygrophoropsis aurantiaca ATCC 28755 v1.0
Annotations/GenomesConol1Conpu1Hygaur1Leumo1SerlaS7_3_2SerlaS7_9_2Serla_varsha1TotalAnnotation Description
Merops
3684323493783623463312,566
42594743816137370Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
10111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11121118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
21251816192221142Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
695444234Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111322313Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
142539Water nucleophile; water bound by Gln and Glu; all endopeptidases
2271222229Families of peptidase inhibitors not assigned to clans
1111116
112217
222711419
522222419Families of metallopeptidases not assigned to clans
1717111115111496Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
7787881257Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
21221916151516124Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
14171615171515109Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
665556538Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
411122112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20182222202120143Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
10106544443Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2215Serine or threonine nucleophile; N-terminal nucleophile
13192114991095Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
121134110105101114109794Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
653344530Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
453433325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
344455126Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
21322969202233226
11
2111117