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Peptidases • Coniochaeta sp. 2T2.1 v1.0
Annotations/GenomesConPMI546Conioc1Conli1Conlig1Lasmin1LecAK0013_1Pilidi1Thiap1TotalAnnotation Description
Merops
3427453293733623083152563,030
2555222529222118217Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
41166451239Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1534171518202716162Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4744333533Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
131112110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1211211110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
22Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
12111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4934747543Water nucleophile; water bound by Gln and Glu; all endopeptidases
12111118Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
4844344435Families of peptidase inhibitors not assigned to clans
2212211213
8844754545
2632531325Families of metallopeptidases not assigned to clans
1225172014221010130Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3422421321Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2321222216Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
918697810875Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1638182123141515160Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
819111312813791Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3733332327Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
121116Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
251212114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2347262824232321215Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
71177443750Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111116Serine or threonine nucleophile; N-terminal nucleophile
2246212521151412176Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
126298114135127102113731,088Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
7228108116476Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3523343326Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1211112110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
221111210Serine nucleophile; catalytic residues in the order Ser, Glu, His
4535223226Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116Families of peptidases of unknown catalytic mechanism not assigned to clans
121111119
12269816101015106
11
11
3333425326