Peptidases • Lecythophora sp. AK0013 v1.0
Annotations/GenomesConPMI546Conli1Conlig1LecAK0013_1Neucr2Podan2ThoPMI491_1TotalAnnotation Description
Merops
3423293733082422959882,877
25222522192167201Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
466552836Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
15171520161841142Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
444333627Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111128Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4344241839Water nucleophile; water bound by Gln and Glu; all endopeptidases
111148Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
444433527Families of peptidase inhibitors not assigned to clans
11
212132213
844514935
11
2323241127Families of metallopeptidases not assigned to clans
12172022121439136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
322224318Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
221222213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
96981071362Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16182114141950152Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
811138101050110Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333344222Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11125Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
212211119Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23262823232233178Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
7774231444Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111137Serine or threonine nucleophile; N-terminal nucleophile
2221251581667174Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
126114135102711044431,095Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
781011563481Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
323423320Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
211138Serine nucleophile; catalytic residues in the order Ser, Glu, His
435243425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
11112118
12981013101577
11
333211325