Peptidases • Helicostylum pulchrum RSA 2064 v1.0
Annotations/GenomesHelpul1Mucci2Parpar1Pilano1Thaele1Zyghet1TotalAnnotation Description
Merops
2793042652612943021,705
212419192331137Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
74344426Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
303530303431190Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
66556533Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
32244217Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
21122210Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
77777742Families of peptidase inhibitors not assigned to clans
1113
1113
11
1111116
22332416
1111116Families of metallopeptidases not assigned to clans
192320202624132Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
44444626Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
14131212121275Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10111010101263Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
612777645Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1211229Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
56556532Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
21322111Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202321192025128Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
23344420Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
1110117111464Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
706761576769391Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
211217Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
65777840Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1311118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
47455530Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115
192420182015116
11
11