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Peptidases • Lophiostoma macrostomum v1.0
Annotations/GenomesAltbr1CocheC5_3Disac1Dotse1Hyspu1Lopma1Mycgr3Sepmu1TotalAnnotation Description
Merops
2823722613194363422862,298
12291017132210113Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
7122484542Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19282625282725178Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
343342322Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
113312314Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
254335224Water nucleophile; water bound by Gln and Glu; all endopeptidases
454355430Families of peptidase inhibitors not assigned to clans
21111118
533563328
264252122Families of metallopeptidases not assigned to clans
131189152818102Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
87334328Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
66687101053Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16261617271719138Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
129610176969Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
333434323Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
4232213Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21202124232121151Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1097386245Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
31111119Serine or threonine nucleophile; N-terminal nucleophile
91691015161186Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
871329112420211997852Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6567118649Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333343322Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
222213315Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
232543423Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
123Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
151512141291188
11
11
33232114