Peptidases • Mortierellomycotina
Annotations/GenomesDisorn1Lobtra1MoeNVP64_1MorGBAus27b_1Morel2Morel_U14_1Morhum1Mormin1_1Mormul1Morve1TotalAnnotation Description
Merops
3212943582864053503113482733223,268
35173513363123261725258Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
555555355548Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
33292825252925282427273Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
668677655561Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11113122214Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111119Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
878788769775Families of peptidase inhibitors not assigned to clans
1112319
21111111110
1113
232312133222
111111321214
141212111115Families of metallopeptidases not assigned to clans
16203818283520351723250Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
535345565546Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
422322323225Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
333333333330Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11101111101212131112113Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1217131413139121215130Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
667677676664Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
234333133227Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
2132111112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
22192118201919191820195Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
465665653652Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
1141310Families of serine peptidases not assigned to clans
17171524191629341724212Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
79728871958666765775765Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
109205182024161022154Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
454554574548Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
343442334131Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
22181923701917172614245
1113