Peptidases • Saccharomyces cerevisiae M3838 v1.0
Annotations/GenomesAscru1Canar1Canca1Canta1Cante1Dekbr2Hanpo2Hypbu1Lipst1_1Metbi1Nadfu1Pacta1_2Picme2Picst3Sacce1SacceM3838_1Spapa3Wican1TotalAnnotation Description
Merops
1551411481491511431511532001421591521341481371361571822,738
10124151065101012610612891812175Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1121111111111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
141216131315141522141613131215151418264Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
92122334223223223451Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11112121111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213Water nucleophile; water bound by Gln and Glu; all endopeptidases
43244343345424224461Families of peptidase inhibitors not assigned to clans
112
112
111115
111121111221116
22222222322222332441
11112112111111117Families of metallopeptidases not assigned to clans
98966661110677697796135Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111111117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1221112121511111125Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
668777867776855576118Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8101312141413121011151411109101019215Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
56337994544973443695Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
34444433434453223362Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191620181818181819162018191720201719330Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3233132423232852351Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111114Serine or threonine nucleophile; N-terminal nucleophile
736333346344333310475Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
313029333427333560292429243525262844576Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
113112112114Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43333333334332333355Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11125Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
33212422525422223450Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22116Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111111111118
8610991199131114988981010171
112
12111326219
22
1113