Peptidases • Pucciniomycotina
Annotations/GenomesAgahy1Atrsp2Chiap1Chicu1Croqu1Eryha1Hetpy1Hyabl1Leucr1MecolCla_1Melame1Melap1finSC_191Melli1Mellp2_3Melme_tre1Melmed1Mereb1Micld1Mixos1Naifl1Naose1Phapa1PuccoNC29_1PuccoSD80_1Pucgr2Pucst1Pucst_PST78_1Pucstr1Puctr1Rhoba1_1Rhodia1_1RhodotJ31_1Rhoglu1Rhoglu91_1Rhomi1Rhomuc1Rhosp1Rhoto1Rhoto_ATCC26217_1Rhoto_IFO0559_1Rhoto_IFO0880_2Rhoto_IFO0880_4Rhoto_IFO1236_1Sepsp1Slopil1Spogra1_1Spoli1Spopa1Sporo1Trisp1TotalAnnotation Description
Merops
17842519718919223217218123042020826117823125625929119018330321035833830519422424437120818516916318017918716916518317217717618517525332122621418015817411,219
11331911271312121441242739262528301630352329584313142129141068991489119111012123337132515117996Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11112118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2411511222111122212122222123232233223223331333221101Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2024181619182221204725341424312519111121201822201322163419201715162013171516141519181920221724141617988Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
37322233251732463224223523353222223222222222322222138Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
114212242252311112112111111148Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111111111211112222212111111111111111113151Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11191111126Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
32333222232423223222445522253322222322122223323333130Families of peptidase inhibitors not assigned to clans
213
112
112
1111111111111215
1111127
112111111112311120
2103123222114636686213177853478322221223133324655211188
123
13121111121111121111111112211122222211111155Families of metallopeptidases not assigned to clans
102598566891268109971013712101013159111717810786696765656711129881016467Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21111111111111121111224Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
151111112218133411341Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11111111111111231121116122121111111111111111111160Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
61467667771176478987467888579146777776677777776866775356Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
827101071488161598498813116121010181310141223911139131013991313111014971499995549Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5146551166141355546513954721101089912610101011108910131214101110591141085438Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111112111111111122211141111111111111148Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6855564651587768855475899557105766665655654555663655306Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111118Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111111118Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19251718231918191837192117172421241917211847372919263039221820181718202017191819191918202121212118171,079Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
311231222422412114338132212123222222222322223525231128Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
311121121111117Serine or threonine nucleophile; N-terminal nucleophile
29467333416595812824841412202014161221121111121113111151224213336Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
461545363548644497113763884377798810559609067907978565262975647444352505645424945494850488912177614333433,281Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
26136228821111314432444322411673315120Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
36333433443333334324333352246534333433323323343544168Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11612112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
221112212112112113312221112222222222212221272Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3444242243211121424211331112422334133333332343122122Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111112111111111121112111111111111111111111150
1220149111213121028151291513171311912153020191618152618111011121312111412121214111421151414101411712
112
211318
11
121112312317