Peptidases • Choiromyces venosus 120613-1 v1.0
Annotations/GenomesAscim1Chove1Lacbi2Pyrco1Terbo1Tubme1Wilmi1TotalAnnotation Description
Merops
2182173382191662171,375
593263762Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
3272418Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192329271823139Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
22992226Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
23111311Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111126Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
2114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
331144429Families of peptidase inhibitors not assigned to clans
1818
112
221117
33232316
21321110Families of metallopeptidases not assigned to clans
1512171381479Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211217Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
21411211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
145Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6101268749Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1210161581879Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
55966536Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
48944433Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
21115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
181923211721119Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
451224330Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
221210951068Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
615774494158340Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
22217Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43432218Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
12622114Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
113117
10112113111379
112
1113
3534318