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Peptidases • Rigidoporus microporus ED310 v1.0
Annotations/GenomesFomme1Onnsc1Porchr1Pornie1_2Ricfib1Ricmel1Rigmic1Schpa1Triab1_1TotalAnnotation Description
Merops
3162943273543433482783303912,981
335938435660253242388Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11122231114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
212122261815181921181Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5641088571063Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
121127Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
33333323326Families of peptidase inhibitors not assigned to clans
112
11111117
23764465542
23442234226Families of metallopeptidases not assigned to clans
131120201612121214130Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111122210Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1199101010910987Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
131010101211181212108Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
89119171299993Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11211111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
76665566552Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1214Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202024272121192222196Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
75684387553Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
8141391816111333135Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
11685113122100108941271371,002Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1148334529Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43335543535Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
32343343328Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111119
311416182235142036206
12115
11