Peptidases • Cytidiella melzeri FP 102339 v1.0
Annotations/GenomesCytmel1Dicsq1Fompi3Phchr2PosplRSB12_1Trave1Wolco1TotalAnnotation Description
Merops
2794073383543344333212,466
35443962476240329Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
214221113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
17161416131516107Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5610364842Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3122210Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
36111122Water nucleophile; water bound by Gln and Glu; all endopeptidases
322522218Families of peptidase inhibitors not assigned to clans
11
11
11111117
33141214
323352422Families of metallopeptidases not assigned to clans
141511914221196Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111139Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11136Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9879109961Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15131615131517104Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
915111011121280Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
565677642Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23222222202224155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
674655538Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11322812233420160Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
93136116127113178105868Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
156346126Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
243254424Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
454443327Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
11521614171322145
11
11
22