Peptidases • Leptosphaeria maculans
Annotations/GenomesAltbr1Bauco1CocheC5_1Dotse1Hyspu1Lepmu1Mycfi2Mycgr3Pyrtr1Pyrtt1Rhyru1Sepmu1Settu1Stano2TotalAnnotation Description
Merops
2822953192603443422973052863243433,397
1213171017221326101613169Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
7544648859767Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1928252228272624252225271Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3335324434337Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
123221131117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111128Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111211111111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2232251123124Water nucleophile; water bound by Gln and Glu; all endopeptidases
4434555545448Families of peptidase inhibitors not assigned to clans
2112112211115
5355333534544
2223322315429Families of metallopeptidases not assigned to clans
13991117281411181216158Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
836247637753Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1211112111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6686101065106780Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1617172124171920192222214Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12131013116121091311120Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3343343333335Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
413332223326Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2121242224211920212121235Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
10235468929866Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
31111111212Serine or threonine nucleophile; N-terminal nucleophile
910101016161314111512136Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
87120124801261199798971141331,195Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6672786662763Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333432233332Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222232232224Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2253133444536Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
213Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
15101481091110111210120
1113
112
12122212114