Peptidases • Macrolepiota fuliginosa MF-IS2 v1.0
Annotations/GenomesAgabi_varbisH97_2Amamu1Copci1Hebcy2Lacbi2Macfu1PleosPC15_2Schco2Trima3TotalAnnotation Description
Merops
2873462872863383363472762,503
2437111632222429195Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
211221211Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
55Water nucleophile; water bound by two Asp
189151729181814138Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3456969446Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2311133822Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1313Water nucleophile; water bound by Gln and Glu; all endopeptidases
46751192347Families of peptidase inhibitors not assigned to clans
18725
112
112228
4155266332
2731323223Families of metallopeptidases not assigned to clans
1913302417273217179Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1211411415Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2111411112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
997812109872Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1812221516171714131Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1012811910101282Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
145Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6675966651Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
241119Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1820192123202027168Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
114871278461Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
610816101012577Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9810599917411512777786Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
226243120Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3324443326Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3634644434Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1552101321152320169
11