Peptidases • Rhizophagus irregularis B3 v1.0
Annotations/GenomesGloin1Lacbi2Morel2Mucci2Phybl2RhiirA1_1RhiirA4RhiirA5RhiirB3Rhimi1_1Tubme1TotalAnnotation Description
Merops
3073384053042843312772932852531663,243
12323624281211911203198Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
4254411124230Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3129253529293130282918314Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4976743446256Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3132354442132Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
211222221116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
51187675657471Families of peptidase inhibitors not assigned to clans
112
1818
213
1113
11
11
121111112112
2121129
11
11
1311111111113Families of metallopeptidases not assigned to clans
201728231723152321188213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1416Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
54223221122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
743435645445Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7121013127666148101Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
121613111518131314118144Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
89712996686686Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111211111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4936544446453Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
22Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11Asparagine nucleophile; all self-processing endopeptidases
123111191161156Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2723202317252026231717238Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
61263394443458Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
5332417Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11114Serine or threonine nucleophile; N-terminal nucleophile
171019101921211917115169Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7874956755847682824641780Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2218182321140Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
7455474446252Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1113322221119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
3647734326247Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
1721702426151516142411253
11
111111219
11
44