Peptidases • Crepidotus variabilis CBS 506.95 v1.0
Annotations/GenomesCorgl3Crevar1Galma1Gymch1Hebcy2Hypsu1TotalAnnotation Description
Merops
3123563883862863792,107
341727501638182Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1111127Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201520201717109Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
751076944Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
35131215Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2125Water nucleophile; water bound by Gln and Glu; all endopeptidases
311935536Families of peptidase inhibitors not assigned to clans
22
2226
46345628
22221211Families of metallopeptidases not assigned to clans
103728202424143Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1311118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
3111118Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
991198955Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10151513151785Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1291210111266Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
2114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55655531Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
192022242120126Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
81110671254Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
152022141620107Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
10412714214491141749Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
4911126850Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34434321Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
44444424Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
241118221313101