Peptidases • Hypoxylon sp. NC0597 v1.0
Annotations/GenomesAntav1Bisnum1DalEC12_1Entma1HyNC0597_1HypEC38_3Xylhyp1TotalAnnotation Description
Merops
4483443553583623753892,631
21181518151619122Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
364234325Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
28172223202222154Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
354344427Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
221211110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11112219Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
335244324Water nucleophile; water bound by Gln and Glu; all endopeptidases
644444531Families of peptidase inhibitors not assigned to clans
11
222221112
436366533
1264444539Families of metallopeptidases not assigned to clans
20191718171715123Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
545555534Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
212121110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
99810781061Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
26252323232524169Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
13171816161715112Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
333344525Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11125Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23232423222122158Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
634656535Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
211211210Serine or threonine nucleophile; N-terminal nucleophile
24212216212217143Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
178112119122136140150957Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
15681210101677Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
344433324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
211211210Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
433344425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
311218Families of peptidases of unknown catalytic mechanism not assigned to clans
21111118
16141418111314100
11
343355427