Peptidases • Calosphaeria pulchella
Annotations/GenomesBotdo1Calpu1Fusox1Maggr1Necha2Neucr2Thite2Trire2Verda1TotalAnnotation Description
Merops
3183375472422562863062,292
20182019261513131Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
329533227Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
16152216152117122Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
233333219Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11211118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
41324620Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
543355328Families of peptidase inhibitors not assigned to clans
11
11
12232212
462141321
235211115Families of metallopeptidases not assigned to clans
1223201291119106Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
45223824Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
121211210Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
88131088762Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
25193514111826148Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
2462810913999Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
123Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
234444425Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
351211Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21212623202325159Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2414234332Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11248Serine or threonine nucleophile; N-terminal nucleophile
2114Families of serine peptidases not assigned to clans
16201989141399Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
115120239718692110833Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
7331576564Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
233232318Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
333423321Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
271212Families of peptidases of unknown catalytic mechanism not assigned to clans
11121118
911131314151388
11
28712222