Peptidases • Dothideomycetes
Annotations/GenomesAaoar1Aciri1_isoAciri1_metaAlikh1Altal1Altalt1Altbr1Altro1Amnli1Ampqui1Aplpr1Ascra1Aulhe2Aurpu_var_mel1Aurpu_var_nam1Aurpu_var_pul1Aurpu_var_sub1AurpulNBB1Bauco1Bimnz1Boeex1Botdo1_1Bysci1Cenge3Cerzm1Clael1Clafu1Clasph1Cloaq1Cocca1CocheC4_1CocheC5_3Coclu2Cocmi1Cocsa1Cocvi1Conap1Corca1Cucbe1Currey1Decga1DelFL0756_1Delco1Delst1Denna1Didex1Didma1Didsa1Dipse1Disac1Dotse1Dotsy1Elsamp1Epini1Erebi1Fenfe1Glonio1Glost2Herpot1_1Horac1Horwer1Hyspu1_1Jahaq1Karrh1Lenfl1Lepmu1Leppa1Linin1Linrh1Lizem1Lophiu1Lopma1Lopmy1Lopnu1Macan1Macph1Macpha1Maseb1Masph1Melpu1Meltu1Micmi1Microd1Mycfi2Mycgr3Myrdu1Myrian1Mytre1Neopa1Ophdi1Parch1Parchr1Parsp1Patat1Perma1PhaPMI808Phapo1Phcit1Phcitr1Phomu1Photr1Phy27169Phycap1Phycit1Phycitr1Phycpc1Pieho1_1Pleav1Plesi1Polci1Polfu1Psehy1Pseule1Pyrly1Pyrsp1Pyrtr1Pyrtt1Rhili1Rhyru1_1Sacpr1Sepmu1Seppo1Setho1Settu3Settur3Spofi1Stano2Stasp1Stely1Stobe1TerNC1134_1Ternu1Totfu1Trepe1Tribi1Tryvi1Venin1Venpi1Veren1Verga1Wesor1Zasce1Zoprh1Zymar1Zymbr1Zymps1TotalAnnotation Description
Merops
40630830521738638128235737730429431631430530932231131729541440739439333435132635029341533534637234132633034726449032832128730327327639333130539530526131930231235727033437737346733754633348042242826034837623731837843637950334840547233935546630639036134434243738640136339045844146025952840840427126435734125426625526526719634035330643630517943443129730547235129028626641332432225034345425742140629938841624835632232935531924859051332430334851,002
1322211715151219242525142017181814181315152613181619201118222229182122228171613171710131823141520101710141712141820161521111717211017231213161320321623241231202034141722232020202525242011172315151518151717151714201212132010102320132628152910102217171613161130251526221619202018171429302420242,645Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
122111111111111118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
108821112710745467878105888733748710101211101010612875681077610424366375763655864578298894910655648648811510101062118953512463441578106281088886538994712466657332275398334962Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
111115Water nucleophile; water bound by two Asp
28272521282719272924222622283025292628292925273030262822292628282124272724292831262727293228232726262527272723342828342047293332312229242627332833293122272926312423302827262728272734343125333131252328252325222326192732212822202828262430222625273422232125321924342828282326191929292633322524253,931Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
44424434542433433334515334323444444424423433443433333533344563446554233433422445234322232544424442245232322343422444443333444334433325243344334122493Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
122311111121322212212112311221111111111111211111331212122132221221322131111311211222121111231112311112114213113111121232111211123221111111121111218Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
322122211111121211211111111221122131231312121323312311212321232211122223322111211111322322111411111122211111211112131189Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1112111111111111111211111211111111111111111147Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111111111111111111111111111111111111111111111111111111111111111111112111111211111111111111111111111111112111111111111111111131Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1322222131154633231223222213551333122212111224333211312133212211113332232314312256251323232145123123314213221112322133111114311141112182626320Water nucleophile; water bound by Gln and Glu; all endopeptidases
544455455555555555455355544545555555554545645535443654455454103554454455565435555445555554544555545445545555555544445555444455444455455555554455545681Families of peptidase inhibitors not assigned to clans
11
11114
11
1111111111121216
11112221111121111111111121111111111111121111112112121111112111121111111111111111111111111111111111111111111122121111111111121111212111111154
5222565464332221239213157225333232317335343431623542426352446765154336553115447533213154584114511461111154342163356432744356365266364365396222525
1113
6331432555541447662105675242265665466164424524434242525333553324883733355744685784593264638349386522752322316443117523743114553463421152103454466222613Families of metallopeptidases not assigned to clans
198912171713131416913111313131313916202522141916181419121211191311131624171114781117141215158917181612161311261024122417161114161116121514201825281714271021141728111117181621191717212418151215151415121513917201222221424201411131981814201210101620103010112218181218151491016212316262,277Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
6177876728212111682516563577777772772434157542358724216163656642283336853454113241124877538771187111111641531777614133877577621133121141444544592Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11121112122221122211221111211111112111111211121112121131112121142112121132111223112221111221112211222222212221112122211111211121122211212212111207Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
688556667557699999676396979876566666686567679758668710675856917778568568117109685867787101088107967869767676676776778787756510561010967675491196658878137978981,048Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3215161324221621262520252817182021201727292227182524202124232426232121191734242120202217262519251916172315252025252334143315282926212027182526272833282426261433262230241720142828262930281732262817182925181918181811222618261483332192029202119202522241922291727201724251915192018201928261517163,269Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
19151481210121510810991079111013131719111210101016141099981111623810111181013101471261059148914161412261017913131413781417181911172214141220816116851414811111281616109913998101010310121515114151112102218109981313711139815109144121012914730174761,687Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1111111111111114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
44434433333333333333333342343333433334333333343333433343333482333333333333333333333343333444333333333233334333332433332333232333244433334433344444464Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111111111111111120Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
22234544342231121143343422223222223321212222333153122152224432221213224333133231324453523143111212315543221211233133311221222122322317Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20232217222121212120241722202020202021242119232224212123212119202221202120202321201921211920192319212420212117212121222441192123212220231820212321222119212122222121232421222122222223222323222423201919201818201918222121242319192320192024