Peptidases • Venturia inaequalis
Annotations/GenomesAplpr1Aulhe2Botdo1Leppa1Macph1Neopa1Patat1Sacpr1Tryvi1Venin1TotalAnnotation Description
Merops
2943143484053632592903563222,951
252017232011291920184Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
56595263243Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
222229222725262619218Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
23522234326Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
23211321116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
21115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
213Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11121111110Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
31131234119Water nucleophile; water bound by Gln and Glu; all endopeptidases
55534545541Families of peptidase inhibitors not assigned to clans
11
112
12112119
311146420
11
517633310341Families of metallopeptidases not assigned to clans
9111425181781218132Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22454312124Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22431221118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
56887668862Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
202820242817211519192Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1091417148101210104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
33333333428Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
232231215Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
242220192223212420195Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32583233433Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11131211213Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
10151513136122619129Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9911711016914678981381241,079Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9381012236659Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
44333333329Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
21222221216Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
43354533131Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
1111308101491112116
11
11331123217