Peptidases • Pycnoporus cinnabarinus CIRM-BRFM 50 v1.0
Annotations/GenomesPycci1Pyccin1Pycco1Pycco1662_1Pycpun1Pycsa1TotalAnnotation Description
Merops
3173413673643013762,066
464454493754284Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22222212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11111412111170Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
53335423Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
123Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1223210Water nucleophile; water bound by Gln and Glu; all endopeptidases
22222212Families of peptidase inhibitors not assigned to clans
1113
22222212
22222212Families of metallopeptidases not assigned to clans
14161618141896Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111126Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
119101081159Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
17161417171495Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1212111191166Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55666634Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
182322222322130Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
45555529Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
252527261829150Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
117134147144106145793Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
54344424Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33332519Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
23334419Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
9111213131472
11
1113