Peptidases • Zygosaccharomyces rouxii CBS732
Annotations/GenomesAscru1Aspnid1Babin1Canar1Canca1Canta1Dekbr2Hanva1_1Klula1Lipst1_1Metbi1Picpa1Sacce1Spapa3Wican1Yarli1Zygro1TotalAnnotation Description
Merops
1552911711411481491431111272001421281371571822121232,717
1041212415665101210818123510189Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
426Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1331121111143Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1410171216131511132214111514181412241Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
9342123322222342248Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211121110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
44Water nucleophile; water bound by Gln and Glu; all endopeptidases
4543243223442443255Families of peptidase inhibitors not assigned to clans
11
112
11
112
1311112212112120
222222323223242237
171111112111111123Families of metallopeptidases not assigned to clans
916138966671066796106140Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111111111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
122211312121112124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
65768776477657675106Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8401410131214111310118910191311226Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5846339255434364579Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
312444414322334246Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1917161620181816201916182017192019308Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
42323114238234143Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111112115Serine or threonine nucleophile; N-terminal nucleophile
743363342633310414381Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
3161453029332721266029262528444421580Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11113111111114Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4133333333333333350Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1212219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
3233214135232342245Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
32117Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111111116
887610911781311991010139158
11
112
1112312112
22
3811141