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Peptidases • Ophiobolus disseminans CBS 113818 v1.0
Annotations/GenomesAltbr1Cocca1CocheC5_3Coclu2Cocmi1Cocsa1Cocvi1Didex1Lepmu1Ophdi1Pyrtr1Pyrtt1Settu1Stano2TotalAnnotation Description
Merops
2823353723413263303473312603902973053243434,583
1222291821222223102513261613272Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
710121110101074108897123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
1926282124272728222726242225346Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3444444455444356Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111111111113Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111112111216Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111111111113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
235133312113129Water nucleophile; water bound by Gln and Glu; all endopeptidases
4555555545555467Families of peptidase inhibitors not assigned to clans
2111111121221118
5332323355354551
2565466438235463Families of metallopeptidases not assigned to clans
1312111913111314111614111216186Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
8777777768767798Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111111111211115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6666666769656788Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1623262321211925212619202222304Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
121099811111013812101311147Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
3334333434333345Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
4222222232223333Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2121202221202120222219202121291Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
108999887588998115Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
31111111111215Serine or threonine nucleophile; N-terminal nucleophile
9161613131416910913141512179Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
871141321271181111251168014997981141331,601Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
67564668212662783Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333333233223339Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2121111122222222Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2334343535344551Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
151215101112141181311101210164
11
2312321122120