Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Suillus cf. sibiricus RUI384 v1.0
Annotations/GenomesSuiame1Suiamp1Suibov1Suibr2Suicli1Suicot1Suidec1Suidis1Suifus1Suigr1Suihi1Suilak1Suilu4Suiocc1Suipal1Suipic1Suipla1Suiplo1Suisib1Suisu1Suisub1Suisubl1Suitom1Suivar1TotalAnnotation Description
Merops
3423613075123273845983353393714003762872913446712853133753503163873583198,948
496351606258254675153736739395435439575966576055501,837Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
12112111212221211211122134Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
152115141726171516161416131318191612171917191514394Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
10910712969778976107610911812139211Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111112121221421Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Water nucleophile; water bound by Gln and Glu; all endopeptidases
22222222623222222222322254Families of peptidase inhibitors not assigned to clans
22
11
111121111111
2322322222211322221222246
22222222222222222222222248Families of metallopeptidases not assigned to clans
111211121717131211121216101411131112191310141314310Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12111112321112111211121132Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1244516124Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11978109781071011811109121010798109220Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161914162219181717141620151720171517251618161622422Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
13111518122015161213141713181616141316147201314350Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111111111111111124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
655555578585555655555576133Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111111111114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
11141212112219Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212022212122232125192221202119222221202221242321514Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5345664446556451255455544121Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1013987121091188781011147811111014108234Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
10112898949112796105105799712280871191219599113106931251051032,489Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
31111351121311131165161151Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3645434484610345445364663114Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1124311Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111111111111111111111124Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
43333434343234333444343380Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111211111121111111227
5020242181526103233010886214021203216183620322951261,065
112
11