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Peptidases • Septoria populicola v1.0
Annotations/GenomesAltbr1Bauco1CocheC5_1Cocsa1Dotse1Hyspu1Lepmu1Mycfi2Mycgr3Pyrtr1Pyrtt1Rhyru1Sepmu1Seppo1Settu1Stano2TotalAnnotation Description
Merops
2822953303192603443422973052862663243433,993
12132217101722132610101613201Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
7510446488539780Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19282725222827262425272225325Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
334353244334344Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12132211321120Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111111210Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11112111111113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
223322511223129Water nucleophile; water bound by Gln and Glu; all endopeptidases
445345555445457Families of peptidase inhibitors not assigned to clans
211121122111117
532553335324548
226233223115436Families of metallopeptidases not assigned to clans
139119111728141118141216183Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
87362476337763Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
121111121111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6668610106510106796Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16172117212417192019202222255Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12131110131161210991311140Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
333433433333341Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
41233322213329Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21212024222421192021212121276Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1028354689249878Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
3111111111214Serine or threonine nucleophile; N-terminal nucleophile
910141010161613141191512159Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8712011112480126119979897871141331,393Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
666727866632772Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333334322333338Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
221222322332228Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
224531334434543Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
12115Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
15101214810911101191210141
1113
112
1321222122119