Peptidases • Penicillium swiecickii 182 6C1 v1.0
Annotations/GenomesPenex1Penexp1Penita1Penla1Penpol1Pensol1Pensoli1Penswi1Penth1TotalAnnotation Description
Merops
3703442482962983653583823182,979
118777149101386Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1121117Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
987678108770Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
343028362836353234293Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33323333326Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22211111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33342443329Water nucleophile; water bound by Gln and Glu; all endopeptidases
44453445437Families of peptidase inhibitors not assigned to clans
1113
11
1111116
11
31231223421
12211243319
76556359248Families of metallopeptidases not assigned to clans
1315981215101511108Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111221212Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
891081091091184Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
332915322230313023245Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
151667813121611104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
43343333329Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22112521117Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
181717211619222322175Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1312781181213993Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11125Serine or threonine nucleophile; N-terminal nucleophile
777555611760Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
13212575961091301261351021,030Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11125121212121513104Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
54433334332Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22222222218Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111115Serine nucleophile; catalytic residues in the order Ser, Glu, His
21222211215Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2313333220Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
141091010913111096
11
1113
121138
32321434123