Peptidases • Homolaphlyctis polyrhiza JEL142 v1.0
Annotations/GenomesAllma1Antlo1Batde5Ganpr1Hompol1Linpe1Lobtra1Parpar1Phybl2Pirfi3Rhihy1Rhimi_ATCC52814_1Rozal1_1Spipu1Zyghet1TotalAnnotation Description
Merops
432293143411842722942652842283602321432103023,890
51036134171928127207831289Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1315Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
422353423432441Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
43119211729293029202228171531351Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1413773657146633590Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
222212314122226Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
211111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112127Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
105555776511744788Families of peptidase inhibitors not assigned to clans
11
22
112
112
1113
22
1124
2113111112115
215131112421
112
2141411411121Families of metallopeptidases not assigned to clans
57235181329202017302515121124328Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
61613262229Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11211321111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1024534335424655Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
167778101212511126912134Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
211111612171710155251041212188Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
111413276791945685Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
7637435555614566Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11125Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
91323311113156Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
331015211621192117171919141925286Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
7553563339265466Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
24112111Serine or threonine nucleophile; N-terminal nucleophile
3032414171119178851014153Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
862441194461726155589848234969889Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1161911311144Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
11553357435537874Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
51133111312212128Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
9361344755454565Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22116Families of peptidases of unknown catalytic mechanism not assigned to clans
3111112111114
24324171915182026153117211515280
211217