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Peptidases • Aspergillus miraensis CBS 140625 v1.0
Annotations/GenomesAspfu1Aspmir1Aspni_NRRL3_1Aspnid1Aspor1TotalAnnotation Description
Merops
2743604042914141,743
471541343Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
134210Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
126933675Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5013371034144Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3343316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
2454318Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
7455425Families of peptidase inhibitors not assigned to clans
11
11
11
11
23139
234110
11
136771447Families of metallopeptidases not assigned to clans
131815162587Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11125Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
43105729Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1736284026147Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
7161681360Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3251112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
2338Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2018201726101Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6894936Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1124Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
83134937Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5911716461153554Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
16111726Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3221715Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
5322315Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
122218Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2323919Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
11111081959
112
11
1113
183038389