Peptidases • Penicillium vulpinum IBT 29486
Annotations/GenomesPenbi1Penbr2Penca1Pench1Pendi1Penex1Penja1Penla1Penra1Penth1Penvul1TotalAnnotation Description
Merops
4453313812952253703592963273182943,641
16899911117101313116Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11112118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
78674911677981Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4137403328343936323425379Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3322335233231Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111111119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111121111213Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
6434335433240Water nucleophile; water bound by Gln and Glu; all endopeptidases
6545445554350Families of peptidase inhibitors not assigned to clans
11
21115
11
21115
2253331344333
2223212113221
95103377562663Families of metallopeptidases not assigned to clans
15111410813108111111122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111112112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1181098878911897Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3230302519332232292322297Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1010121161513710117112Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
5454243433441Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22223111216Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2018232018182121192220220Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1069851310811911100Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111122111Serine or threonine nucleophile; N-terminal nucleophile
7797577577573Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
193109133926713212896107102951,254Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9151410411131291313123Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4455253353443Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222223222223Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
3221121222220Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22111233217Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
161515108141310111014136
11114
1113
3343333251232