Peptidases • Hyalopycnis blepharistoma ATCC 48560 v1.0
Annotations/GenomesAgahy1Chiap1Croqu1Eryha1Hetpy1Hyabl1Melli1Mellp1Mixos1Pucgr1Pucst1Rhoba1_1Rhomi1Rhosp1Sporo1Trisp1TotalAnnotation Description
Merops
1781971922321721811781832241851871651581742,606
11192713121239301410149117228Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2115111122322125Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2018191822211411222013151617246Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3322333232322235Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
142121112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3332222223223334Families of peptidase inhibitors not assigned to clans
111115
112
11114
2323223133121129
11111111111112Families of metallopeptidases not assigned to clans
10956681071110971016124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211111121213Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111111122111115Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6666774477677585Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8107148846141113995126Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5651166559108108599Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
6556467457555575Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1917231918191717261820171817265Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3212221322223128Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
247333581612121370Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4653548644494360524756423343708Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
216223241528Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3334333225334445Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2111212121216Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3424221414432238Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111111111112
12141112131299181112141411172
213
11
1135