Peptidases • Pisolithus
Annotations/GenomesPisalb1Piscro1Pismar1Pismi1Pismi2Pismi_AB1_1Pisori2Pisthe1Pisthe227_1Pisti1Pisti2TotalAnnotation Description
Merops
2392733173092632482192692763062452,964
1721243525162219183826261Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1232121222220Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1516181314131216141514160Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6323433333336Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
421421122120Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
99161111888131217122Families of peptidase inhibitors not assigned to clans
5111210
111231111214
3222222222223Families of metallopeptidases not assigned to clans
101213918121315151513145Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111121321115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1113Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
989108128981010101Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1625312020182122241616229Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11181018181491615910148Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1121111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
71165555996573Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111116Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11111117Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1828241927341925312019264Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5435343543342Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
52119Serine or threonine nucleophile; N-terminal nucleophile
54105445655558Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
6370936162615671726765741Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1211121221115Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4654544564451Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3434643342339Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111111111
2019167119221421196418303
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