Peptidases • Aspergillus clavatus NRRL 1 from AspGD
Annotations/GenomesAspac1Aspbr1Aspca3Aspcl1Aspfo1Aspni5Aspnid1Aspsy1Asptu1Aspve1Aspwe1Eurhe1Pench1TotalAnnotation Description
Merops
3583994092733722914073734283642442954,213
131617912461261889130Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1434113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
107841033281033777164Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
313338413510203319383133362Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33333333323234Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2131111111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
1111116Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
65626436233450Water nucleophile; water bound by Gln and Glu; all endopeptidases
55555545496563Families of peptidase inhibitors not assigned to clans
11215
1113
11
11
11
11121321321321
6443445331340
101067979101357396Families of metallopeptidases not assigned to clans
101418151416221519191210184Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
891178568764988Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
282724222540382541251625336Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11201451681215168811144Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
45435125233441Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1121117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
3224415Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
221923222017191819202020239Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
561197469997890Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
12112119Serine or threonine nucleophile; N-terminal nucleophile
101111711459496794Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
138168166771496114015014112670921,478Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
61065416781011074Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43223153554542Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22212232321224Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1111217Serine nucleophile; catalytic residues in the order Ser, Glu, His
21321211112118Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2233322118Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111112
910139108101010111210122
1225
112
1113
3213833381073135