Peptidases • Acremonium strictum DS1bioAY4a v1.0
Annotations/GenomesAcrst1Fusve1Ilysp1Necha2Trias1Triat2Triha1Trilo3TotalAnnotation Description
Merops
4816775473604004692723,206
17232019202215136Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
9129373144Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19312218201918147Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
343334323Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11212119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
143898639Water nucleophile; water bound by Gln and Glu; all endopeptidases
443344426Families of peptidase inhibitors not assigned to clans
112
11
11
2212119
11211129
22
3125213127Families of metallopeptidases not assigned to clans
22292014211911136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1455333336Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
25111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1081381010867Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
36363523242416194Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
27332813161714148Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
444444529Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
555112120Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23282623252322170Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
716145511462Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
232336423Serine or threonine nucleophile; N-terminal nucleophile
22251926312714164Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
211312239137140208851,332Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1037311415177131Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333333321Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
343333322Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1214Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
913131318181599
11
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