Peptidases • Penicillium chrysogenum Wisconsin 54-1255
Annotations/GenomesPenbi1Penbr2Penca1Pench1PenchWisc1_1Pendi1Penex1Penfe1Pengl1Penla1Penra1TotalAnnotation Description
Merops
4453313812953172253703934142963273,794
16899209111112710122Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111126Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
78679498106781Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4137403335283435413632392Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3322333322329Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111112111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
6434333664345Water nucleophile; water bound by Gln and Glu; all endopeptidases
6545444555552Families of peptidase inhibitors not assigned to clans
21115
21111118
225323323429
2223321321122
95103337855664Families of metallopeptidases not assigned to clans
15111410108131014811124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1181091088778995Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3230302528193330293229317Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10101211116151711710120Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
5454324544343Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111110Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22122121114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2018232022181821192119219Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
10698851391181198Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111129Serine or threonine nucleophile; N-terminal nucleophile
7797657795776Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
193109133929567132160174961071,358Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9151410941189129110Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4455525343545Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222222222222Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
3221112222220Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
221111214318Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
16151510138149121011133
1112117
11114
33432331062544