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Peptidases • Trametes polyzona CIRM-BRFM 1798 v1.0
Annotations/GenomesArtel1Artele1122_1Pyccin1Pycpun1Pycsa1Traci1Tragib1Tralj1Trapol1Trapub1Trave1TotalAnnotation Description
Merops
3773533413013763443383523424114333,968
6339443754444349495662540Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2222211111116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1415111111111311131415139Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
9735445444453Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11125Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
113222221117Water nucleophile; water bound by Gln and Glu; all endopeptidases
2222212222221Families of peptidase inhibitors not assigned to clans
111111118
2222222221221
2222222222222Families of metallopeptidases not assigned to clans
1716161418171517192722198Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111110Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11121112111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111310Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
989811109879997Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1515161714172217181615182Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101112911121111121712128Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5656667554762Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
2423232322222123222322248Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4555544556553Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2222251829242225232834272Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1491501341061451351321421281651781,564Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
4344422445642Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3332543333436Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2334434432335Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111216Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
109111314118891513121
1111127